“Over-expressed fat-producing genes and increased glucose transport into cells,” is the conclusion of a study looking at artificial sweeteners. Metabolic dysfunction and excessive fat accumulation and inflammation is something many if not most people would prefer to avoid.
Researchers looked at the effect of artificial sweeteners (mainly Sucralose and a trace of aspartame, and/or acesulfame potassium) upon stem cells taken from human fat cells to arrive at this conclusion. The amount of Sucrolose was estimated to be equivalent to about 4 cans of diet soda per day–admittedly a high consumption of the artificial sweetener. In both healthy weight and obese people, researchers observed:
- Increased sugar transport into cells,
- Overexpression of known fat-producing genes,
- Overexpression of sweet taste receptors in fat tissue,
- Increased expression of genes that produce inflammation,
- Increased accumulation of fat droplets in cells.
So what does this mean for individuals who opt to utilize artificial sweeteners in their personal struggle with weight, blood sugar, or the plethora of secondary conditions which are worsened by generalized inflammation in the body?
Fortunately, there are many healthy (and less sweet) foods and products from which one can opt to obtain their nutrition.
And for pleasure one may revert to certain herbs and spices, sauces, and dressings to enhance food taste and palatability.
For example, many people add cinnamon and/or cream to their coffee instead of sweetener.
Perhaps a healthy rule-of-thumb would be to consume an equivalent quantity of sweets that one’s great, great, great, great… grandmother or grandfather consumed (prior to the mass production of refined sugar, sugary processed foods, or artificial sweeteners).
Fortunately unlike vitamins, minerals, essential fats, and protein (essential amino acids) which are foundational for human health, ‘sweetness’, to a large degree appears to be optional, non essential, and indeed, an impediment.